Pálffy or Palffy is a Hungarian surname which means "son of Pál". Notable people with the surname include:
Žigmund Pálffy (born 1972), Slovak ice hockey playerDavid Palffy (born 1969), Canadian actor of Hungarian extractionLipót Pálffy de Erdőd (1764–1825), Major GeneralFerdinand Palffy von Erdöd (1774–1840), mining engineer in the Austrian Empire and Vienna Theatre managerFidél Pálffy (1895–1946), Hungarian nobleman who was a leading supporter of Nazism in HungaryJános Pálffy (1664–1751), Hungarian noble, Imperial Field marshal and Palatine of Hungary