ATC code A03AA01 (WHO) PubChem CID 4642 UNII 4V44H1O8XI Pubchem 4642 ChemSpider ID 4481 | CAS Number 125-53-1 IUPHAR/BPS 7256 Molar mass 344.45 g/mol ChEMBL ID 1200891 IUPHAR/BP 7256 | |
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AHFS/Drugs.com International Drug Names | ||
Oxyphencyclimine is an antimuscarinic.
Synthesis
Reaction of chloroacetonitrile (1) with methanol and hydrogen chloride leads to the corresponding iminoether (Pinner reaction). Condensation of 2 with 3-methylaminopropylamine gives (3) gives the corresponding tetrahydropyrimidine (4). Displacement of the halogen with the sodium salt 5 affords oxyphencyclimine (6).
References
Oxyphencyclimine Wikipedia(Text) CC BY-SA