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Oxalate oxidase

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EC number
  
1.2.3.4

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9031-79-2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, an oxalate oxidase (EC 1.2.3.4) is an enzyme that catalyzes the chemical reaction

oxalate + O2 + 2 H+ 2 CO2 + H2O2

The 3 substrates of this enzyme are oxalate, O2, and H+, whereas its two products are CO2 and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is oxalate:oxygen oxidoreductase. Other names in common use include aero-oxalo dehydrogenase, and oxalic acid oxidase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It has 2 cofactors: FAD, and Manganese.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1FI2, 2ET1, 2ET7, and 2ETE.

References

Oxalate oxidase Wikipedia


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