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Oxalate decarboxylase

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EC number
  
4.1.1.2

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9024-97-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Oxalate decarboxylase

In enzymology, an oxalate decarboxylase (EC 4.1.1.2) is an enzyme that catalyzes the chemical reaction

oxalate + H+ formate + CO2

Thus, the two substrates of this enzyme are oxalate and H+, whereas its two products are formate and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is oxalate carboxy-lyase (formate-forming). This enzyme is also called oxalate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1UW8, 2UY8, 2UY9, 2UYA, and 2UYB.

References

Oxalate decarboxylase Wikipedia