Osipov (Russian: Осипов), Osipova (feminine; Осипова), or Ossipoff is a Russian surname. Notable people with the surname include:
Afanasiy Osipov (1928), a Soviet painter and People's Artist of the RSFSR
Alexei Osipov (1938 -), Russian Orthodox theologian and professor
Alexander Osipov (1920-1945), a Soviet aircraft pilot and Hero of the Soviet Union
Eskandar Shura Ossipoff, a former Assyrian boxerwho Iran at the 1948 Summer Olympics
Fyodor Osipov (1902-1989), a Soviet army officer and Full Cavalier of the Order of Glory
Gennady Osipov (1929), a Soviet sociologist and academician
Gennady Simeonovich Osipov (1948-?), a Russian scientist in Artificial Intelligence, professor
Irina Osipova (1981-), a Russian basketball player
Maria Osipova (1908-1999), a member of the Soviet underground and Hero of the Soviet Union
Mikhail Osipov (1918-1943), a Soviet aircraft pilot and Hero of the Soviet Union
Natalia Osipova (born 1985-) is a Russian ballerina
Nikolai Osipov (1901-1945), a Russian balalaika virtuoso, conductor, pedagogue, and People's Artist
N. P. Osipov (1751-1799), a Russian writer, poet, and translator
Osipov State Russian Folk Orchestra
Pyotr Osipov (1900-1987), a Soviet writer
Taisiya Osipova (1984-) is a Russian opposition activist
Tatyana Osipova (1987-) is a Kazakhstani cross country skier
Vasily Osipov (1917-1991), a Soviet aircraft pilot and double Hero of the Soviet Union
Vasily Ivanovich Osipov (1918-1944), a Soviet army officer and Hero of the Soviet Union
Vasily Vasilyevich Osipov (1920-1989), a Soviet aircraft pilot and Hero of the Soviet Union
Viktor Osipov (1871-1947), a Russian psychiatrist and academician
Vladimir Ossipoff (1907–1998), an American architect best known for his works in Hawaii
Yevgeni Osipov (disambiguation), multiple people
Yury Osipov (b. 1936), the President of the Russian Academy of Sciences since 1991.