Osei is both an Ashanti surname and an Ashanti given name. Notable people with the Ashanti name include:
Surname:
Emmanuel Osei (born 1981), Ghanaian association football playerEmmanuel Osei Kuffour (born 1976), Ghanaian association football playerKennedy Osei (born 1966), Ghanaian middle distance runnerKevin Osei (born 1991), French-born Ghanaian association football playerRansford Osei (born 1990), Ghanaian professional association football playerMikki Osei Berko, Ghanaian actorNana Osei Bonsu II (born 1939), Regent of the Ashanti KingdomOtumfuo Nana Osei Tutu II (born 1950), AsanteheneGiven name:
Osei Bonsu (died 1824), AsanteheneOsei Kofi Tutu I (died 1717), founder of the Ashanti ConfederacyOsei Kwadwo, Ashanti kingOsei Kwame Panyin, AsanteheneOsei Sankofa (born 1985), English association football playerOsei Parris (born 2000), Dutch student