Oscar Ruffini (1858–1957) was an architect in San Angelo, Texas.
He worked some with architect brother Frederick Ernst Ruffini.
A number of his works are listed on the U.S. National Register of Historic Places.
Works include (with attribution):
Concho County Courthouse, Public Sq. Paint Rock, TX Ruffini, F.E. and Ruffini, Oscar
Crockett County Courthouse, 907 Ave. D Ozona, TX Ruffini, Oscar
Harris Drug Store, 114 S. Chadbourne St. San Angelo, TX Ruffini, Oscar
Mason-Hughes House, 1104 W. Beauregard San Angelo, TX Ruffini, Oscar
Montgomery Ward Building, 10 W. Beauregard San Angelo, TX Ruffini, Oscar
J. J. Rackley Building, 118 S. Chadbourne San Angelo, TX Ruffini, Oscar
San Angelo National Bank, Johnson and Taylor, and Schwartz and Raas Buildings, 20–22, 24, 26 E. Concho Ave. San Angelo, TX Lillis, Ruffini & Ruffini
Sutton County Courthouse, Public Sq. Sonora, TX Ruffini, Oscar
Tom Green County Jail, US 67 San Angelo, TX Ruffini, Oscar