Oropeza is a Spanish surname. Notable people with the surname include:
Ana Teresa Oropeza (born (1964), Miss Venezuela for 1982
Enrique Priego Oropeza, Mexican politician
Renato Prada Oropeza (born 1937), Bolivian-Mexican scientist, literary researcher and writer
Jenny Oropeza (1957-2010), California State Senator
Jorge Oropeza (born 1983), Mexican footballer
Juan Oropeza (1906–1971), Venezuelan lawyer, diplomat, writer, educator and political science expert
Sam Oropeza (born 1985), American mixed martial artist
Luis José Oropeza, Venezuela, (born 1946) poeta, writer ecology expert
