PubChem CID 10697702 Formula C27H43NO7S Molar mass 525.696 g/mol | ChemSpider 8873045 3D model (Jmol) Interactive image | |
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Synonyms 2β-(2,2-Dimethyl-4-morpholinyl)-3α-hydroxy-11,20-dioxo-5α-pregnan-21-yl methanesulfonate |
Org 21465 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABAA receptor positive allosteric modulator. It is similar to related drugs such as Org 20599, and was similarly developed as an improved alternative to other sedative steroids such as althesin and allopregnanolone, which despite its superior properties in some respects has not proved to offer enough advantages to be accepted into clinical use.
References
Org 21465 Wikipedia(Text) CC BY-SA