Rahul Sharma (Editor)

Org 21465

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PubChem CID
  
10697702

Formula
  
C27H43NO7S

Molar mass
  
525.696 g/mol

ChemSpider
  
8873045

3D model (Jmol)
  
Interactive image

Org 21465 httpsuploadwikimediaorgwikipediacommonsthu

Synonyms
  
2β-(2,2-Dimethyl-4-morpholinyl)-3α-hydroxy-11,20-dioxo-5α-pregnan-21-yl methanesulfonate

Org 21465 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABAA receptor positive allosteric modulator. It is similar to related drugs such as Org 20599, and was similarly developed as an improved alternative to other sedative steroids such as althesin and allopregnanolone, which despite its superior properties in some respects has not proved to offer enough advantages to be accepted into clinical use.

References

Org 21465 Wikipedia