Orford is a surname. Notable people with the surname include:
John Orford, British classical bassoonist
Lewis Orford (1865–1948), English lawyer and cricketer
Martin Orford, keyboard player of the progressive rock band IQ
Matt Orford, Australian rugby league footballer
Robert Orford, English Bishop of Ely from 1302 to 1310
Sandy Orford (1911–1986), Welsh rugby league player and wrestler