Oprah's Angel Network was a charity organized in 1998 and involved in various projects such as education supplies, school construction, disaster relief, and other areas.
In May 2010, with Oprah's show ending, the charity stopped accepting donations and was shut down.
As of February 2016 donations to the Oprah Winfrey Leadership Academy Foundation which supports the Oprah Winfrey Leadership Academy for Girls can be made via a page on eBay with PayPal.
References
Oprah's Angel Network Wikipedia(Text) CC BY-SA