Opoku is both an Ashanti given name and an Ashanti surname. Notable people with the Ashanti name include:
Colleen Opoku Amuaben (born 1960), general superintendent
Dorcas Opoku Dakwa (or Abrewa Nana) (born 1980), Ghanaian singer, songwriter and dancer
Eric Opoku-Agyemang (or Eric Opoku) (born 1991), Ghanaian footballer
Jonathan Opoku (born 1990), Dutch professional footballer
Jordan Opoku (born 1983), Ghanaian footballer
Joshua Drew Opoku Okoampa (or Joshua Okoampa) (born 1984), American soccer player
Joshua Otto Opoku (or Joshua Otto) (born 1990), Ghanaian footballer
Naana Jane Opoku-Agyemang (born 1951), Ghanaian academic
Nana Opoku Agyemang-Prempeh (or Agyemang Opoku) (born 1989), Ghanaian footballer
Prince Opoku Bismark Polley Sampene (or Prince Polley) (born 1969), Ghanaian footballer
Samuel Opoku Nti known as Opoku Nti (born 1961), Ghanaian footballer
Stanley Opoku Aborah (or Stanley Aborah) (born 1987), Ghanaian-Belgian professional footballer
Richard Opoku Osei (or Richard Osei) (born 1985), Ghanaian footballer
Given name
Opoku Ware I (1700–1750), Asantehene
Opoku Ware II (1919–1999), fifteenth King of the Empire of Ashanti
Opoku Afriyie, Ghanaian footballer and manager
