Opie is both a surname and a given name. Notable people with the name include:
Alan Opie, (born 1945), baritone singerAmelia Opie (1769-1853), English author - wife of John OpieCatherine Opie, (born 1961), American artist and photographerEugene Lindsay Opie (1873-1971), American pathologistIona Opie, (born 1923), specialist in children's literature, and the customs of schoolchildren - wife of Peter OpieJohn Opie, (1761-1807), Cornish historical and portrait painter - husband of Amelia OpieJulian Opie, British artist, famed for his use of vector-based reproductionsLisa Opie, (born 1963), English squash playerOpie Ortiz, artist specializing in tattoos, pop art and muralsOpie Cates, (1909-1987), American clarinet playerPeter Opie, (1918-1982) English specialist in children's literature, and the customs of schoolchildren - husband of Iona OpieRedvers Opie (1900-1984) British economistRobert Opie, British item collector and director of the Museum of Brands, Packaging and Advertising