Ono (小野) and Ōno (大野) is a Japanese surname. Ono means "small field" and Ōno means "large field". Both are used as Japanese surnames. The following people were born in Japan, unless otherwise noted:
Ono no Azumabito (d. 757), a Japanese court official during the Nara period, governor of Bizen province
Ōno no Azumabito (d. 742), an official, during the same period, who held the Imperial position of Chinjufu-shogun
Chizu Ono, a photographer
Daisuke Ono, a voice actor
Frank H. Ono, a Japanese-American soldier
Ōno Harunaga, a general under Toyotomi Hideyori
Hitoshi Ono, a rugby player
Jiro Ono (chef) (born 1925), chef of Sukiyabashi Jiro, a three-Michelin-starred Japanese restaurant
Kazushi Ono, an orchestra and opera conductor
Ken Ono, a Japanese-American mathematician
Kōsei Ono, a rugby player
Ōno Kurobei, a chief retainer of the Banshū Akō Domain
Lisa Ono, a Japanese-Brazilian bossa nova singer
Machiko Ono, actress
Marina Ōno, a voice actress
Masatoshi Ono, a rock/heavy metal singer
Minoru Ōno, the real name of Saburō Kitajima, an Enka singer
Ryōko Ono, a voice actress
Ryumo Ono, Japanese basketball player
Santa J. Ono, a Japanese-American biologist, university administrator and Board member
Shinji Ono, a footballer
Shinjiro Ono, a former deputy commissioner of the Japan Patent Office
Shunzo Ono, a footballer
Susumu Ōno, a linguist
Takashi Ono (born 1931), a gymnast and Olympic medalist
Takashi Ono (judoka) (born 1980), a martial arts practitioner
Takashi Ono (mathematician) (born 1928), number theorist
Toshihiro Ono, a manga artist
Yoko Ono, a musician, artist, feminist and peace activist who married John Lennon
Yūki Ōno, a wrestler