Routes of
administration IV Synonyms TRV130 PubChem CID 66553195 | ATC code none CAS Number 1401028-24-7 | |
 | ||
Legal status US: Investigational New Drug | ||
Oliceridine (TRV130) is an opioid drug that is under evaluation in human clinical trials for the treatment of acute severe pain. It is a functionally selective, G protein biased μ-opioid receptor agonist developed by Trevena Inc. Oliceridine elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less β-arrestin 2 recruitment and receptor internalization, it displays fewer adverse effects than morphine.
References
Oliceridine Wikipedia(Text) CC BY-SA