Oikonomou (Greek: Οικονόμου), also transliterated as Ikonomou and Economou, is a Greek surname, deriving from the word oikonomos, "housekeeper, steward". It can refer to:
Aikaterini Oikonomou, birth name of Ketty Diridaoua, Greek actress
Antonis Oikonomou, naval captain in the Greek War of Independence
Carlie Ikonumou, Australian association football player
Constantin von Economo, Austrian neurologist
Demetris Economou, Cypriot association football player
Dimitrios Oikonomou, Greek admiral
Eleftherios Oikonomou, Greek Chief of Police
Evangelos Ikonomou, Greek association football player
George Economou (poet), American poet
George Economou (Shipbuilder), Greek billionaire shipowner
George A. Economou, Sr., optical systems expert
James S. Economou, surgical oncologist, tumor immunologist, and Vice Chancellor for Research at the UCLA
Manthos Oikonomou, Greek scholar and Ali Pasha's advisor
Marios Oikonomou, Greek football player
Michalis Oikonomou, Greek impressionist painter
Nicolas Economou, Cypriot composer
Nick Economou, Australian political scientist
Nikos Ekonomou, Greek basketball player
Panajotis Iconomou, Greek-German baritone
Pavlos Oikonomou-Gouras, Greek diplomat
Stav Economou, English mixed martial artist
Thanasis Oikonomou, Greek swimmer
Thomas Oikonomou, Greek actor