Ofori is an Ashanti surname. Notable people with the Ashanti surname include:
David Ofori-Adjei (born 1949), Ghanaian physician and medical researcher
Kofi Asante Ofori-Atta, Ghanaian politician
Nana Ofori-Twumasi (born 1990), English footballer
Nana Sir Ofori Atta I (1881–1943), Okyenhene, king of Akyem Abuakwa kingdom
Peter Ofori-Quaye (born 1980), Ghanaian footballer
Prince Ofori (born 1988), Ghanaian-Beninese footballer
William Ofori Atta (1910–1988), Ghanaian lawyer and politician