Odile is a feminine given name of French origin. The name refers to:
Odile of Cologne (c. 4th century), a saint of the Roman Catholic Church
Odile of Alsace (c. 662 - c. 720), a saint of the Roman Catholic Church
Odile Crick (1920–2007), British artist best known for her drawing of the DNA double helix
Odile Defraye (1888–1965), Belgian road-racing bicyclist
Odile Gilbert (contemporary), French hairstylist
Odile Harington (born 1961), South African intelligence agent
Odile Jacob (contemporary), French scientist who studies the workings of the brain
Odile Lesage (born 1969), French heptathlete
Odile Saugues (born 1943), French left-wing politician