Species Human Entrez 3175 | Human Mouse Ensembl ENSG00000169856 | |
Aliases ONECUT1, HNF-6, HNF6, HNF6A, one cut homeobox 1 External IDs MGI: 1196423 HomoloGene: 3309 GeneCards: ONECUT1 | ||
One cut homeobox 1 is a protein that in humans is encoded by the ONECUT1 gene.
Function
This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.
References
ONECUT1 Wikipedia(Text) CC BY-SA