Nye is a surname of Anglo-Saxon origin. Notable people with the surname include:
Sir Archibald Nye, British military officer
Ben Nye, Hollywood makeup artist
Bill Nye, U.S. popular scientist and TV personality
Carrie Nye, U.S. actress
David Evelyn Nye, 20th century British architect
David E. Nye, U.S. historian
David Nye, British racing driver
Edd Nye, North Carolina politician
Edgar Wilson Nye, "Bill" Nye, 19th century U.S. humorist
Frank Nye, U.S. congressman from Minnesota
George D. Nye, U.S. Democratic politician
Gerald Nye, U.S. Senator and political activist
Glenn Nye, U.S. Democratic congressman from Virginia
James W. Nye, 19th century U.S. senator
Jody Lynn Nye, U.S. science fiction author
Joseph Nye, U.S. academic and political theorist
Lee Nye, U.S. photographer
Liam Nye, British entrepreneur
Louis Nye, U.S. actor and comedian
Naomi Shihab Nye, Palestinian-American poet and songwriter
Nye Lavalle, American Social Scientist & Sports Marketing Executive
Robert Nye (1939–2016), British novelist, poet and playwright
Russel Blaine Nye, American author and historian of popular culture
Ruth Nye, Australian pianist
Simon Nye, British comedy writer, creator of sitcom Men Behaving Badly
Steve Nye, music producer
Michael Joseph Nye, 4.3.1998, British Proffesional Counter Strike: Global Offensive gamer/Professional Racing Driver