Nobili is an Italian surname. Notable people with the surname include:
Anna Maria Nobili, Italian physicist
Brian Nobili (born 1976), American photographer
Bruno Nobili (born 1949), Italian-Venezuelan footballer and manager
Durante Nobili, 16th-century Italian painter
Elena Nobili (1833–1900), Italian painter
John Nobili (1812–1856), Italian Roman Catholic priest
Leopoldo Nobili (1784–1835), Italian physicist
Riccardo Nobili (1859–1939), Italian painter, writer and antiquarian
Simone Nobili (born 1991), Italian model
Tito Oro Nobili (1882–1967), Italian politician
