Trisha Shetty (Editor)

Nitromethaqualone

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ATC code
  
none

PubChem CID
  
63339

Molar mass
  
311.29

ChemSpider ID
  
57006

CAS Number
  
340-52-3

Formula
  
C16H13N3O4

3D model (Jmol)
  
Interactive image

Nitromethaqualone httpsuploadwikimediaorgwikipediacommonsthu

Nitromethaqualone is an analogue of methaqualone that has similar sedative and hypnotic properties. It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25 mg. However, the aromatic nitro group is metabolised to the corresponding aniline, which proved to be a mutagen. As a consequence, nitromethaqualone was not developed further due to toxicity concerns.

References

Nitromethaqualone Wikipedia