EC number 1.7.2.5 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37256-43-2 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a nitric-oxide reductase (EC 1.7.2.5) is an enzyme that catalyzes the chemical reaction
2 nitric oxide + electron donorThe 2 substrates of this enzyme are nitric oxide and electron donor, whereas its three products are nitrous oxide, oxidized electron donor/acceptor, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with other acceptors. The systematic name of this enzyme class is nitrous-oxide:acceptor oxidoreductase (NO-forming). Other names in common use include nitrogen oxide reductase, and nitrous-oxide:(acceptor) oxidoreductase (NO-forming). This enzyme participates in nitrogen metabolism and in the microbial defense against nitric oxide toxicity.
Structural studies
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1EHE, 1F24, 1F25, 1F26, 1JFB, 1JFC, 1ULW, and 1XQD.