Nishimoto is a Japanese surname. Notable people with the surname include:
Joe M. Nishimoto (1919–1944), American soldier and recipient of the Medal of Honor
Kaoru Nishimoto (1924–2012), Japanese shogi player
Katsuko Nishimoto (born 1950), Japanese politician of the Liberal Democratic Party (LDP)
Takeshi Nishimoto (born 1974), Japanese guitarist and composer
Tatsuhiro Nishimoto (born 1980), Japanese football player
Tetsuo Nishimoto (born 1950), Japanese volleyball player
Tomomi Nishimoto (born 1970), Japanese conductor
Yukio Nishimoto (1920–2011), Japanese Baseball player
