Nishimoto is a Japanese surname. Notable people with the surname include:
Joe M. Nishimoto (1919–1944), American soldier and recipient of the Medal of HonorKaoru Nishimoto (1924–2012), Japanese shogi playerKatsuko Nishimoto (born 1950), Japanese politician of the Liberal Democratic Party (LDP)Takeshi Nishimoto (born 1974), Japanese guitarist and composerTatsuhiro Nishimoto (born 1980), Japanese football playerTetsuo Nishimoto (born 1950), Japanese volleyball playerTomomi Nishimoto (born 1970), Japanese conductorYukio Nishimoto (1920–2011), Japanese Baseball player