Sneha Girap (Editor)

Niles Pierce

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Name  Niles Pierce

Niles Pierce httpss3uswest1amazonawscombbeprodstorag

Education  University of Oxford (1997)
Awards  Guggenheim Fellowship for Natural Sciences, US & Canada
Similar  Erik Winfree, Paul W K Rothemund, Georg Seelig, Jehoshua Bruck, Eric Klavins

Niles A. Pierce is an American mathematician, bioengineer, and professor at the California Institute of Technology. He is a leading researcher in the fields of DNA computing and DNA nanotechnology. His research is focused on kinetically controlled DNA and RNA self-assembly. Pierce is working on applications in bioimaging.

Pierce graduated from Princeton University in 1993 with a BSE in Mechanical & Aerospace Engineering. He attended Oxford University as a Rhodes Scholar, completing a DPhil in Applied Mathematics in 1997. He joined the faculty of the California Institute of Technology in 2000.

Works

  • Next-generation in situ hybridization chain reaction: higher gain, lower cost, greater durability H.M.T. Choi, V.A. Beck, and N.A. Pierce ACS Nano 8(5):4284-4294, 2014.
  • Conditional Dicer substrate formation via shape and sequence transduction with small conditional RNAs L.M. Hochrein, M. Schwarzkopf, M. Shahgholi, P. Yin, and N.A. Pierce J Am Chem Soc 135(46):17322-17330, 2013.
  • Nucleic acid sequence design via efficient ensemble defect optimization J.N. Zadeh, B.R. Wolfe, and N.A. Pierce J Comput Chem 32:439-452, 2011.
  • NUPACK: Analysis and design of nucleic acid systems J.N. Zadeh, C.D. Steenberg, J.S. Bois, B.R. Wolfe, M.B. Pierce, A.R. Khan, R.M. Dirks, and N.A. Pierce J Comput Chem 32:170-173, 2011.
  • Programmable in situ amplification for multiplexed imaging of mRNA expression H.M.T. Choi, J.Y. Chang, L.A. Trinh, J.E. Padilla, S.E. Fraser, and N.A. Pierce Nature Biotechnol 28:1208-1212, 2010.
  • Programming biomolecular self-assembly pathways P. Yin, H.M.T. Choi, C.R. Calvert, and N.A. Pierce Nature 451:318-322, 2008.
  • Thermodynamic analysis of interacting nucleic acid strands R.M. Dirks, J.S. Bois, J.M. Schaeffer, E. Winfree, and N.A. Pierce SIAM Rev 49(1):65-88, 2007.
  • Triggered amplification by hybridization chain reaction R.M. Dirks and N.A. Pierce Proc Natl Acad Sci USA 101(43):15275-15278, 2004.
  • A synthetic DNA walker for molecular transport J.-S. Shin and N.A. Pierce J Am Chem Soc 126:10834-10835, 2004.
  • References

    Niles Pierce Wikipedia