Nichole is a feminine given name and has also been used as a surname. Notable people with the name include:
Nichole Bloom (born 1989), American actress and model
Nichole de Carle, British fashion designer best known for her lingerie and swimwear brand
Nichole Cheza (born 1987), American motorcycle racer
Nichole Denby (born 1982), US-born Nigerian track and field athlete
Nichole Hiltz (born 1978), American actress
Nichole Mead (born 1988), American beauty pageant titleholder
Nichole Millage (born 1977), American Paralympic volleyball player
Nichole Nordeman (born 1972), American Christian singer–songwriter
Kimberly Nichole, American singer-songwriter and actress