Negroni is an Italian/Corsican surname. Notable people with the surname include:
Daniele Negroni (1995), an Italian singer and runner-up on Deutschland sucht den Superstar (season 9)Héctor Andrés Negroni, military officer, historian, aerospace senior executiveJoe Negroni, founding member of the rock and roll group Frankie Lymon and the TeenagersJean Negroni, narrator in French film La JetéeLuca Negroni (born 1964), Italian ski mountaineerGeneral Pascal Olivier Count de Negroni, Led the charge of Cuirassiers in the Battle of Reichshoffen during the Franco-Prussian War of 1870.