Species Human Entrez 4775 | Human Mouse Ensembl ENSG00000072736 | |
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Aliases NFATC3, NFAT4, NFATX, nuclear factor of activated T-cells 3 External IDs MGI: 103296 HomoloGene: 27827 GeneCards: NFATC3 | ||
Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene.
Function
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene.
References
NFATC3 Wikipedia(Text) CC BY-SA