Species Human Entrez 55247 | Human Mouse Ensembl ENSG00000109674 | |
Aliases NEIL3, FGP2, FPG2, NEI3, ZGRF3, hFPG2, hNEI3, nei like DNA glycosylase 3 External IDs MGI: 2384588 HomoloGene: 10094 GeneCards: NEIL3 | ||
Nei endonuclease VIII-like 3 (E. coli) is a protein in humans that is encoded by the NEIL3 gene.
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
References
NEIL3 Wikipedia(Text) CC BY-SA