Species Human Entrez 252969 | Human Mouse Ensembl ENSG00000154328 | |
Aliases NEIL2, NEH2, NEI2, nei like DNA glycosylase 2 External IDs MGI: 2686058 HomoloGene: 17032 GeneCards: NEIL2 | ||
Endonuclease VIII-like 2 is an enzyme that in humans is encoded by the NEIL2 gene.
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002)[supplied by OMIM]
References
NEIL2 Wikipedia(Text) CC BY-SA