Species Human Entrez 4741 | Human Mouse Ensembl ENSG00000104722 | |
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Aliases NEFM, NEF3, NF-M, NFM, neurofilament, medium polypeptide External IDs HomoloGene: 38041 GeneCards: NEFM | ||
Neurofilament medium polypeptide (NF-M) is a protein that in humans is encoded by the NEFM gene.
Function
Neurofilaments are type IV intermediate filament heteropolymers composed of light (NEFL), medium (this protein), and heavy (NEFH) chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage.
References
NEFM Wikipedia(Text) CC BY-SA