Entrez 374291 | Ensembl ENSG00000115286 | |
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Aliases NDUFS7, CI-20, CI-20KD, MY017, PSST, NADH:ubiquinone oxidoreductase core subunit S7 External IDs MGI: 1922656 HomoloGene: 11535 GeneCards: NDUFS7 | ||
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, also knowns as NADH-ubiquinone oxidoreductase 20 kDa subunit, is an enzyme that in humans is encoded by the NDUFS7 gene. The NDUFS7 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.
Structure
The PSST subunit is highly conserved across evolutionary distances. Crystal structures and mutational studies indicate that it is one of the ubiquinone binding sites of Complex I, together with the TYKY (NDUFS8) subunit.
References
NDUFS7 Wikipedia(Text) CC BY-SA