Trisha Shetty (Editor)

NDRG2

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Species
  
Human

Entrez
  
57447

Human
  
Mouse

Ensembl
  
ENSG00000165795

NDRG2

Aliases
  
NDRG2, SYLD, NDRG family member 2

External IDs
  
MGI: 1352498 HomoloGene: 22785 GeneCards: NDRG2

Protein NDRG2 is a protein that in humans is encoded by the NDRG2 gene (NMYC downstrean-regulated gene 2).

Function

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma and aggressive meningioma carcinogenesis (via cell proliferation). Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

References

NDRG2 Wikipedia