Species Human Entrez 24142 | Human Mouse Ensembl ENSG00000243477 | |
Aliases NAT6, FUS-2, FUS2, N-acetyltransferase 6 External IDs MGI: 1888902 HomoloGene: 36325 GeneCards: NAT6 | ||
N-acetyltransferase 6 (GCN5-related) is a protein that in humans is encoded by the NAT6 gene.
Function
This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl-CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3, and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011].