Species Human Entrez 4678 | Human Mouse Ensembl ENSG00000132780 | |
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Aliases NASP, FLB7527, PRO1999, HMDRA1, nuclear autoantigenic sperm protein External IDs MGI: 1355328 HomoloGene: 133894 GeneCards: NASP | ||
Nuclear autoantigenic sperm protein is a protein that in humans is encoded by the NASP gene. Multiple isoforms are encoded by transcript variants of this gene.
Function
This gene encodes a histone H1 binding protein that is involved in transporting histones into the nucleus of dividing cells. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
References
NASP (gene) Wikipedia(Text) CC BY-SA