Girish Mahajan (Editor)

N1 acetylpolyamine oxidase

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EC number
  
1.5.3.13

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

N1-acetylpolyamine oxidase (EC 1.5.3.13, hPAO-1, mPAO, hPAO) is an enzyme with systematic name N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming). This enzyme catalyses the following chemical reaction

(1) N1-acetylspermidine + O2 + H2O ⇌ putrescine + 3-acetamidopropanal + H2O2 (2) N1-acetylspermine + O2 + H2O ⇌ spermidine + 3-acetamidopropanal + H2O2

This enzyme also catalyses the reaction:

N1,N12-diacetylspermine + O2 + H2O ⇌ N1-acetylspermidine + 3-acetamamidopropanal + H2O2.

References

N1-acetylpolyamine oxidase Wikipedia
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