Supriya Ghosh (Editor)

N hydroxyarylamine O acetyltransferase

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EC number
  
2.3.1.118

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
100984-92-7

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a N-hydroxyarylamine O-acetyltransferase (EC 2.3.1.118) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + an N-hydroxyarylamine CoA + an N-acetoxyarylamine

Thus, the two substrates of this enzyme are acetyl-CoA and N-hydroxyarylamine, whereas its two products are CoA and N-acetoxyarylamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N-hydroxyarylamine O-acetyltransferase. Other names in common use include arylhydroxamate N,O-acetyltransferase, arylamine N-acetyltransferase, and N-hydroxy-2-aminofluorene-O-acetyltransferase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1E2T.

References

N-hydroxyarylamine O-acetyltransferase Wikipedia