Molar mass 308.434 g/mol | ||
 | ||
Appearance Colourless Waxy Semi-Solid | ||
n-Octyl β--thioglucopyranoside (octylthioglucoside, OTG) is a detergent that is used for cell lysis or to solubilise membrane proteins without denaturing them. This is particularly of use in order to crystallise them or to reconstitute them into lipid bilayers. It has a critical micelle concentration of 9 mM.
It is an analog of the commonly used detergent octyl glucoside, the presence of the thioether linkage making it resistant to degradation by beta-glucosidase enzymes.
References
N-Octyl beta-D-thioglucopyranoside Wikipedia(Text) CC BY-SA