Trisha Shetty (Editor)

Myospherulosis

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Myospherulosis, also known as spherulocytosis, is a foreign body-type granulomatous reaction to lipid-containing material and blood.

It may be seen in various settings including:

  • Fat necrosis.
  • Malignancy, e.g. renal cell carcinoma.
  • Placement of topical tetracycline in a petrolatum base into a surgical site.
  • The resultant histopathologic pattern is most unusual and initially was mistakenly thought to represent a previously undescribed endosporulating fungus.

    References

    Myospherulosis Wikipedia