Muse is a surname. Notable people with the surname include:
Abduwali Muse (born c. 1990), Somali pirateAlexander Muse (born 1972), American businessmanArizona Muse (born 1988), American fashion modelC. Anthony Muse (born 1958), American politicianGeorge and Willie Muse, African-American circus performers and the subject of the 2016 book TruevineJohn Muse (born 1988), American ice hockey playerJohn Muse (businessman), American businessmanMunirudeen Adekunle Muse (born 1939), Nigerian politicianSunday Muse, Canadian actress and voice actressWilliam Muse (born 1939), American university president