Muse is a surname. Notable people with the surname include:
Abduwali Muse (born c. 1990), Somali pirate
Alexander Muse (born 1972), American businessman
Arizona Muse (born 1988), American fashion model
C. Anthony Muse (born 1958), American politician
George and Willie Muse, African-American circus performers and the subject of the 2016 book Truevine
John Muse (born 1988), American ice hockey player
John Muse (businessman), American businessman
Munirudeen Adekunle Muse (born 1939), Nigerian politician
Sunday Muse, Canadian actress and voice actress
William Muse (born 1939), American university president
