Mouse or The Mouse is the nickname of:
Gordon Cleaver (died 1994), British Second World War flying ace
Mouse Davis (born 1932), American football coach and player
William B. Evans, Commissioner of the Boston Police Department beginning 2014
Edward Fielden (RAF officer) (1903–1976), Royal Air Force air vice-marshal
Curt Malawsky (born 1970), Canadian former box lacrosse player and current head coach
Ed Mierkowicz (born 1924), American former Major League Baseball player
Mouse Morris (born 1951), Irish racehorse trainer and jockey
Edgar Munzel (1907–2002), American sportswriter nicknamed "The Mouse"
Mouse Randolph (1909–1997), American swing jazz trumpeter
Bruce Strauss (born 1952), American retired journeyman boxer nicknamed "The Mouse"
Micheen Thornycroft (born 1987), Zimbabwean Olympic rower
Daniel Zaragoza (born 1957), Mexican retired boxer known as "The Mouse"