Most is a surname. Some notable people with the surname include:
Deforrest Most (1917-2006), American gymnast
Don Most (born 1953), American actor
Doug Most (born 1968), editor of The Boston Globe Magazine
Glenn W. Most (born 1952), American classicist and comparatist
Jeff Most (born 1960), American film producer
Johann Most (1846–1906), German-American anarchist and orator
Johnny Most (1923–1993), American sports announcer
Mickie Most (1938–2003), English record producer
Sam Most (born 1930), Los Angeles-based jazz flautist and tenor saxophonist
