Mosbacher is a surname. Notable people with the surname include:
Robert Mosbacher (1927–2010), American businessman, United States Secretary of Commerce, yachtsman
Georgette Mosbacher (born 1947), American businesswoman and Republican fundraiser; former wife of Robert
Dee Mosbacher (born 1949), American filmamker and lesbian feminist, daughter of Robert
Robert Mosbacher, Jr. (born 1951), American businessman and Republican politician; former head of the Overseas Private Investment Corporation; son of Robert
