Monkhouse is a surname. Notable people with the surname include:
Alan Monkhouse (1930–1992), English footballerAllan Monkhouse (1858–1936), English playwright, critic, essayist and novelistAmy Monkhouse (born 1979), lawn bowlerAndy Monkhouse (born 1980), English footballerBob Monkhouse, OBE (1928–2003), English entertainerGraham Monkhouse (born 1954), former English cricketerMichelle Monkhouse (1991–2011), Canadian fashion modelSteve Monkhouse (born 1962), former English cricketerWilliam Cosmo Monkhouse (1840–1901), English poet and critic