Missy or Missie is a feminine first name, often a short form of Melissa.
People:
Michele Avila (1968-1985), American murder victimMissie Berteotti (born 1963), American LPGA golferMissy Cummings, Associate Professor of Aeronautics and Astronautics at the Massachusetts Institute of Technology and former U.S. Navy fighter pilotMissy Elliott (born 1971), American rapper, singer, songwriter and record producerMissy Giove (born 1972), American former professional mountain bike riderMissy Gold (born 1970), American former child actressMissy Franklin (born 1995), American competitive swimmerMissy Higgins (born 1983), Australian singer and songwriterMissy Hyatt (born 1963), American professional wrestling valetMissy LeHand (1898–1944), longtime private secretary to U.S. President Franklin D. RooseveltMissy Malone, British burlesque performerMissy Mazzoli (born 1980), American composer and pianistMissie McGeorge (born 1959), American LPGA golferMissy Peregrym, Canadian actressMissy Raines (born 1962), American bluegrass bassistMissy Robbins (born 1971), American chefMissy Schwen-Ryan (born 1972), American rowerOther:
Missy (cow), the most expensive cow in the worldMissy (short for The Mistress), a female incarnation of the villain The Master from the British science fiction series Doctor Who