Puneet Varma (Editor)

Mir BART2 microRNA precursor family

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Symbol
  
mir-BART2

miRBase
  
MI0001068

Domain(s)
  
Viruses

Rfam
  
RF00364

RNA type
  
Gene; miRNA

GO
  
0035195 0035068

Mir-BART2 microRNA precursor family

The mir-BART2 microRNA precursor found in Human herpesvirus 4 (Epstein-Barr virus) and Cercopithicine herpesvirus 15. mir-BART2 is expressed in all stages of infection but expression is significantly elevated in the lytic stage. In Epstein-Barr virus, mir-BART2 is found in the intronic regions of the BART (Bam HI-A region rightward transcript) gene whose function is unknown. mir-BART2 is thought to target the virally encoded DNA polymerase BALF5 for degradation. The mature sequence is excised from the 5' arm of the hairpin.

References

Mir-BART2 microRNA precursor family Wikipedia