Symbol mir-625 miRBase family MIPF0000534 Domain(s) Eukaryota; | Rfam RF01017 RNA type microRNA | |
In molecular biology mir-625 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. Many microRNAs play important roles in cancer development and progression.
mir-625 and gastric cancer
mir-625 has been shown to be down regulated in gastric cancers. This is important, as mir-625 is responsible for the regulation of metastasis in gastric tumour cells, and therefore downregulation of mir-625 results in increased metastasis. mir-625 is thought to act by inhibiting the ILK protein.
References
Mir-625 microRNA precursor family Wikipedia(Text) CC BY-SA