Suvarna Garge (Editor)

Mir 196 microRNA precursor family

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Symbol
  
mir-196

miRBase
  
MI0000238

RNA type
  
Gene; miRNA

Rfam
  
RF00256

miRBase family
  
MIPF0000031

Domain(s)
  
Eukaryota

Mir-196 microRNA precursor family

miR-196 is a non-coding RNA called a microRNA that has been shown to be expressed in human (MI0000238, MI0000279) and mouse (MI0000552, MI0000553). miR-196 appears to be a vertebrate specific microRNA and has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000031). In many species the miRNA appears to be expressed from intergenic regions in HOX gene clusters. The hairpin precursors are predicted based on base pairing and cross-species conservation—their extents are not known. In this case the mature sequence is excised from the 5' arm of the hairpin.

It has been suggested that a rare SNP (rs11614913) that overlaps has-mir-196a2 has been found to be associated with non-small cell lung carcinoma.

References

Mir-196 microRNA precursor family Wikipedia