Mikes is a surname. Notable persons with the surname include:
Christos Mikes (born 1971), retired Greek footballerÉva Mikes (1938-1986), Hungarian pop singerGeorge Mikes (1912–1987), Hungarian-born British authorKelemen Mikes (1690–1761), Hungarian political figureMihály Mikes (died 1662), Chancellor of Transylvania from 1656 to 1660Mihály Mikes (soldier) (died 1721), Hungarian landowner and aristocratMike Mikes, American soccer player